Skimmianine attenuates liver ischemia/reperfusion injury by regulating PI3K–AKT signaling pathway-mediated inflammation, apoptosis and oxidative stress
Abstract Liver ischemia/reperfusion (I/R) injury is a common injury after liver transplantation and laguna 3hp dust collector hepatectomy.Skimmianine (Ski) has antibacterial, antiviral pharmacological effects.However, it is not clear whether Ski has a protective effect against liver I/R injury.In the present study, we established a mouse liver I/R